drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody (bispecific T‑cell engager) immunotherapy
drug_description
Subcutaneous bispecific T‑cell–engaging monoclonal antibody that binds BCMA on malignant plasma cells and CD3 on T cells to redirect T‑cell cytotoxicity against BCMA‑positive myeloma cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Bispecific
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Subcutaneous
drug_mechanism_of_action
Bispecific T‑cell–engaging monoclonal antibody that binds BCMA on myeloma/plasma cells and CD3 on T cells, forming an immune synapse that activates and redirects T‑cell cytotoxicity (perforin/granzyme) to kill BCMA‑positive cells.
drug_name
Elranatamab (Elrexfio)
nct_id_drug_ref
NCT06711705