drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Polyclonal antibody preparation that depletes T cells for GVHD prophylaxis.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antithymocyte Globulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Cytotoxic protein
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal anti–human T-cell immunoglobulin that binds multiple T-cell surface antigens and depletes T cells via complement-dependent lysis and Fc-mediated ADCC/phagocytosis, reducing alloreactive T cells to prevent GVHD.
drug_name
Antithymocyte Globulin (ATG)
nct_id_drug_ref
NCT06378060