drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Polyclonal antibody preparation that depletes T lymphocytes for induction immunosuppression.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antithymocyte Globulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Cytotoxic protein
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal anti–T-lymphocyte IgG that binds multiple T-cell surface antigens and depletes T cells via complement-dependent cytotoxicity and Fc-mediated ADCC, with additional T-cell apoptosis and functional inhibition, producing potent immunosuppression.
drug_name
Antithymocyte globulin (ATG)
nct_id_drug_ref
NCT06305286