drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
An anti-HER2 antibody–drug conjugate that binds HER2 (ERBB2), is internalized, and releases the microtubule inhibitor MMAE to induce mitotic arrest and apoptosis.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Disitamab Vedotin
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-HER2 monoclonal antibody linked to MMAE. Binds HER2 (ERBB2) on tumor cells, is internalized, and releases the microtubule inhibitor MMAE intracellularly, causing mitotic arrest and apoptosis.
drug_name
Disitamab vedotin (RC48)
nct_id_drug_ref
NCT06420973