drug_type
RELEVANT_DRUG
intervention_type
Biological (bispecific antibody; T-cell engager)
drug_description
An intravenously administered bispecific T-cell–engaging antibody that binds CD19 on B cells and CD3 on T cells, forming an immune synapse and activating TCR/CD3 signaling to drive T-cell–mediated cytotoxicity against malignant CD19+ B cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Injections
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Intravenous
drug_mechanism_of_action
Intravenous bispecific antibody that binds CD19 on B cells and CD3 on T cells, creating an immune synapse that activates TCR/CD3 signaling and redirects T-cell cytotoxicity to eliminate malignant CD19+ B cells.
drug_name
YK012
nct_id_drug_ref
NCT06565689