drug_type
RELEVANT_DRUG
intervention_type
Biologic (monoclonal antibody)
drug_description
B-cell–depleting monoclonal antibody that removes CD20+ B cells via ADCC, CDC, and apoptosis, generally sparing long-lived plasma cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody targeting CD20 on B cells that depletes CD20+ B cells via antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and apoptosis, generally sparing long-lived plasma cells.
drug_name
Anti-CD20 monoclonal antibody
nct_id_drug_ref
NCT06384976