drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Intravenous bispecific monoclonal antibody (T‑cell engager) that binds BCMA on plasma cells and CD3 on T cells, redirecting T‑cell cytotoxicity to deplete pathogenic plasma cells and reduce amyloidogenic light‑chain production in systemic AL amyloidosis. Also known as REGN5458; brand name Lynozyfic.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Intravenous
drug_mechanism_of_action
Bispecific monoclonal antibody that binds BCMA on plasma cells and CD3 on T cells, redirecting T‑cell cytotoxicity to deplete BCMA+ plasma cells and reduce amyloidogenic light‑chain production in AL amyloidosis.
drug_name
Linvoseltamab
nct_id_drug_ref
NCT06292780