drug_type
RELEVANT_DRUG
intervention_type
Biological (monoclonal antibody immunotherapy)
drug_description
Investigational anti-HER2 monoclonal antibody intended to inhibit HER2 signaling and promote immune-mediated cytotoxicity (e.g., ADCC) in HER2-expressing tumors.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
IAH0968 is an anti‑HER2 monoclonal antibody that binds HER2/ERBB2 on tumor cells, inhibits HER2 signaling (e.g., prevents receptor activation/dimerization), and promotes immune‑mediated killing via antibody‑dependent cellular cytotoxicity (ADCC), leading to death of HER2‑expressing cancer cells.
drug_name
IAH0968
nct_id_drug_ref
NCT06504732