gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells recognize CD19 on target cells and directly kill them via NK-cell cytotoxicity (perforin/granzyme release and death-receptor pathways), with IL-15 supporting activation and persistence.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR scFv-mediated recognition on B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06707259
disease_id_num_tar_ref
1
drug_id_num_tar_ref
1