gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine delivers neoantigen peptides to APCs, priming CD4+ and CD8+ T cells. These T cells then recognize the neoantigen–MHC complexes on tumor cells and kill them via perforin/granzyme or Fas–FasL pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA-DR/DP/DQ on APCs; primes CD4+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06344156
disease_id_num_tar_ref
116
drug_id_num_tar_ref
310