gene_symbol
ULBP3
hgnc_id
HGNC:14895
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D on the infused double‑negative T cells binds ULBP3 on target cells, triggering MHC‑independent cytotoxicity via perforin/granzyme release (and IFN‑γ), leading to target cell apoptosis/lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05858814
disease_id_num_tar_ref
1100
drug_id_num_tar_ref
2999