gene_symbol
ULBP4
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
RC1012 DNT cells express NKG2D and recognize ULBP4 (an NKG2D ligand) on target cells, triggering MHC-independent killing via perforin/granzyme-mediated cytolysis and IFN-γ release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05858814
disease_id_num_tar_ref
1100
drug_id_num_tar_ref
2999