gene_symbol
MICB
hgnc_id
HGNC:7091
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-NK cells recognize MICB on target cells, triggering NK activation and perforin/granzyme-mediated cytolysis (with possible death receptor signaling), killing the MICB+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand (stress-induced)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05776355
disease_id_num_tar_ref
1126
drug_id_num_tar_ref
3073