gene_symbol
ULBP1
hgnc_id
HGNC:14893
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR‑NK cells bind ULBP1 on target cells, triggering NK activation and degranulation with perforin/granzymes, leading to target cell lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand (stress-induced)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05776355
disease_id_num_tar_ref
1126
drug_id_num_tar_ref
3073