gene_symbol
ULBP2
hgnc_id
HGNC:14894
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-NK cells bind ULBP2 on target cells, activating NK degranulation and killing via perforin/granzyme-mediated apoptosis (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand (stress-induced)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05776355
disease_id_num_tar_ref
1126
drug_id_num_tar_ref
3073