gene_symbol
ULBP3
hgnc_id
HGNC:14895
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-NK cells recognize ULBP3 via the NKG2D-based CAR, activate, and directly lyse target cells through perforin/granzyme release (and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand (stress-induced)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05776355
disease_id_num_tar_ref
1126
drug_id_num_tar_ref
3073