gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Dendritic cell vaccine primes/expands EBV (including LMP1)-specific CD8+ T cells, which recognize LMP1-derived peptides on MHC I of EBV-positive cells and kill them via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
EBV latent antigen; presented via MHC class I/II by autologous DCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05882305
disease_id_num_tar_ref
1180
drug_id_num_tar_ref
3229