gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine-primed EBV-specific CD8+ T cells recognize LMP2B-derived peptides on MHC I of EBV+ cells and kill them via perforin/granzyme-mediated cytolysis (with CD4+ T-cell help).
enzyme_product
Off
epitope
On
variant
Off
isoform
On
hla_specific
On
gated
Off
other_modifier
EBV latent antigen; presented via MHC class I/II by autologous DCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05882305
disease_id_num_tar_ref
1180
drug_id_num_tar_ref
3229