gene_symbol
CDH17
hgnc_id
HGNC:1756
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CDH17 CAR-T cells bind CDH17 on target cells, become activated, and kill them via T cell effector mechanisms (perforin/granzyme-mediated apoptosis and death receptor pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface epithelial cadherin expressed on CDH17-positive solid tumors
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06501183
disease_id_num_tar_ref
127
drug_id_num_tar_ref
338