gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific antibody links CD3 on T cells to BCMA on target cells, forming an immune synapse and activating TCR/CD3 signaling; engaged T cells kill BCMA+ cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05955508
disease_id_num_tar_ref
133
drug_id_num_tar_ref
364