gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR T cells bind CD19 on target cells and trigger T-cell cytotoxicity, lysing targets via perforin/granzyme-mediated apoptosis (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-lineage cell surface antigen (naive/memory B cells, plasmablasts)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06691152
disease_id_num_tar_ref
1208
drug_id_num_tar_ref
3295