gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-HBs IgG binds HBsAg on infected hepatocytes; Fc engages FcγR+ effector cells to mediate ADCC (and can activate complement/CDC), leading to lysis of HBsAg-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Binds HBsAg on HBV virions and SVPs; can opsonize HBsAg on HBV-infected hepatocytes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05293158
disease_id_num_tar_ref
1211
drug_id_num_tar_ref
3298