gene_symbol
FCGR2A
hgnc_id
HGNC:3616
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
HBIG opsonizes HBsAg on infected hepatocytes; its Fc binds FCGR2A on immune effector cells to trigger ADCC/ADCP that kills the hepatocytes, not the FCGR2A-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Myeloid Fcγ receptor contributing to effector functions (ADCC/ADCP)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05293158
disease_id_num_tar_ref
1211
drug_id_num_tar_ref
3298