gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific antibody binds CD3 on T cells to activate them and bridge to BCMA on tumor cells; T cells then kill BCMA+ targets via perforin/granzyme. CD3+ T cells are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05955508
disease_id_num_tar_ref
133
drug_id_num_tar_ref
364