gene_symbol
FOLR1
hgnc_id
HGNC:3791
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
MOv18 IgE binds FRα on tumor cells and engages FcεRI/CD23 on immune effector cells, inducing ADCC/ADCP and cytotoxic degranulation that kills FRα-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface tumor antigen on FRα-positive ovarian cancer cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06547840
disease_id_num_tar_ref
1230
drug_id_num_tar_ref
3332