gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CARCIK-CD19 cells recognize CD19 on target cells via the CAR, become activated, and kill the CD19+ cells through perforin/granzyme-mediated cytotoxicity (and related T-cell effector mechanisms).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen targeted by CAR scFv
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05869279
disease_id_num_tar_ref
1265
drug_id_num_tar_ref
3421