gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-PSMA antibody (rosopatamab) labeled with lutetium-177 binds PSMA on tumor cells and emits beta radiation at the cell surface, causing DNA double-strand breaks and lethal damage (apoptosis/mitotic catastrophe).
enzyme_product
On
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface metallopeptidase
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06520345
disease_id_num_tar_ref
1307
drug_id_num_tar_ref
3536