gene_symbol
CD274
hgnc_id
HGNC:17635
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind PD-L1 via the CAR, activating T-cell cytotoxicity and killing PD-L1–expressing cells through perforin/granzyme-mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
checkpoint ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06084286
disease_id_num_tar_ref
1308
drug_id_num_tar_ref
3540