gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR T cells bind CD19 and, via CD3ΞΆ/4-1BB signaling, are activated to kill CD19+ cells through perforin/granzyme release and death-receptor pathways (HLA-independent).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05807789
disease_id_num_tar_ref
1309
drug_id_num_tar_ref
3544