gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-expressing T cells recognize CD19 on target cells and directly kill them via cytotoxic T-cell mechanisms (perforin/granzyme release and Fas/FasL-mediated apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR-mediated recognition of B-cell surface antigen; non-HLA restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05432635
disease_id_num_tar_ref
1313
drug_id_num_tar_ref
3558