gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CMV peptide antigens engage the native CMV-specific TCRs to restimulate and expand the engineered T cells; actual killing is mediated by the anti-CD19 CAR against CD19+ cells, not by recognition of CMV peptides.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–HLA complexes recognized by endogenous CMV-specific TCRs; vaccine boosts recall responses
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05432635
disease_id_num_tar_ref
1313
drug_id_num_tar_ref
3558