gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The DC vaccine primes/expands neoantigen-specific CD8+ T cells, which recognize the GBM neoantigen peptides on HLA class I and kill the tumor cells via CTL cytotoxicity (perforin/granzyme, Fas–FasL).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ T-cell targets (MHC I)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05100641
disease_id_num_tar_ref
8
drug_id_num_tar_ref
16