gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific antibody binds CD3 on T cells and CD20 on B cells, forming an immune synapse that activates T cells to kill CD20+ lymphoma cells (perforin/granzyme, FasL). CD3+ T cells are not killed by the drug.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
monovalent binding on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06552572
disease_id_num_tar_ref
1317
drug_id_num_tar_ref
3569