gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-directed CAR T cells bind BCMA on target cells, become activated, and kill them via perforin/granzyme-mediated cytolysis (and related death pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CD269; TNF receptor superfamily member expressed on plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT07028970
disease_id_num_tar_ref
1321
drug_id_num_tar_ref
3576