gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR T cells recognize CD19 on target cells and, upon activation, kill them via perforin/granzyme cytolysis and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; dual-target CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT07097207
disease_id_num_tar_ref
1324
drug_id_num_tar_ref
3582