gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The anti-CD38 ADC binds CD38+ cells, is internalized, and releases an MMAF payload that inhibits tubulin polymerization, causing G2/M arrest and apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen on plasma cells targeted by the antibody moiety
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05692908
disease_id_num_tar_ref
1364
drug_id_num_tar_ref
3701