gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused autologous T cells use endogenous TCRs to recognize the HLA-presented neoantigen on malignant cells and kill them via perforin/granzyme-mediated cytolysis (and related T cell effector pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide-HLA complex recognized by endogenous TCRs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06559644
disease_id_num_tar_ref
158
drug_id_num_tar_ref
429