gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 CAR-T cells bind CD20 on target cells and induce T-cell cytotoxicity, primarily via perforin/granzyme-mediated apoptosis (with additional Fas/FasL and cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-cell antigen targeted by CAR scFv
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06313957
disease_id_num_tar_ref
1411
drug_id_num_tar_ref
3811