gene_symbol
CLEC12A
hgnc_id
HGNC:31713
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CLL-1 on target cells; CAR signaling activates T-cell cytotoxicity, killing targets via perforin/granzyme-mediated apoptosis (and associated immune effector mechanisms).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as MICL; CD371
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05995041
disease_id_num_tar_ref
1423
drug_id_num_tar_ref
3844