gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells engineered to target CD19 bind the antigen and, upon CAR signaling, kill CD19+ cells via perforin/granzyme release (and death receptor pathways), leading to apoptosis/lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-target CAR-T with CD20
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06517004
disease_id_num_tar_ref
167
drug_id_num_tar_ref
453