gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and triggers killing via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity (through FcγR-expressing effector cells), and direct induction of apoptosis upon CD20 crosslinking.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06176729
disease_id_num_tar_ref
1471
drug_id_num_tar_ref
3978