gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific binds CD3 on T cells to engage and activate them against CLDN6-positive tumor cells; activated T cells kill the CLDN6-expressing tumor cells (perforin/granzyme), not the CD3+ effector cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Second arm of bispecific engages an immune effector receptor to activate cytotoxic attack
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06681870
disease_id_num_tar_ref
1484
drug_id_num_tar_ref
4018