gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the tumor-associated peptide presented by HLA class II via their native TCRs (CD4+ T cells) and kill the presenting cells through perforin/granzyme-mediated cytolysis and Fas–FasL–induced apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC class II complex recognized by CD4+ TIL TCR; HLA allele–restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06530303
disease_id_num_tar_ref
1498
drug_id_num_tar_ref
4045