gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine induces/expands CMV pp65–specific T cells; CTLs recognize pp65-derived peptides on MHC I of CMV-expressing cells and kill them via perforin/granzyme cytotoxicity (with CD4+ T-cell help).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
MHC class II–restricted epitopes within pp65
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06132438
disease_id_num_tar_ref
1533
drug_id_num_tar_ref
4137