gene_symbol
CTAG1B
hgnc_id
HGNC:2491
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered TCR-T cells recognize the NY-ESO-1(157–165) peptide presented on HLA-A*02 and kill target cells via TCR-triggered perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC class I complex; HLA-A2 (e.g., A*02:01) restriction
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05881525
disease_id_num_tar_ref
1561
drug_id_num_tar_ref
4224