gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine peptides are presented by dendritic cells on HLA-A2 to prime CD8+ T cells; the induced CTLs then recognize corresponding TAA epitopes on tumor cells and kill them via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Microbiome-derived HLA-A2–restricted epitopes; 5 distinct TAA mimics
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05589597
disease_id_num_tar_ref
1565
drug_id_num_tar_ref
4234