gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG includes antibodies against CD11a; binding to CD11a+ cells triggers complement-dependent cytotoxicity and Fc-mediated ADCC, with additional apoptosis, leading to depletion of those cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin alpha-L; adhesion molecule
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05482542
disease_id_num_tar_ref
1586
drug_id_num_tar_ref
4295