gene_symbol
B2M
hgnc_id
HGNC:914
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
rATG recognizes multiple T‑cell antigens and depletes T cells via complement-dependent cytotoxicity, ADCC, and apoptosis; beta‑2‑microglobulin is not a defined target, so B2M+ cells are not directly targeted or killed by rATG.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
MHC class I light chain component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05482542
disease_id_num_tar_ref
1586
drug_id_num_tar_ref
4295