gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 mAb binds CD20 on B cells and triggers complement-dependent cytotoxicity and Fc-mediated ADCC by NK/macrophages, and can directly induce apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; large extracellular loop epitope
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05482542
disease_id_num_tar_ref
1586
drug_id_num_tar_ref
4296