gene_symbol
CD33
hgnc_id
HGNC:1659
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells bind CD33 on target cells, triggering NK activation and killing via degranulation (perforin/granzyme) and death-receptor pathways (FasL/TRAIL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06367673
disease_id_num_tar_ref
1602
drug_id_num_tar_ref
4337